Successfully managed case of rhabdomyosarcoma of bladder and prostate with poor response to intensive chemotherapy and obstructive uropathy

Rhabdomyosarcoma ( ) is the commonest soft tissue sarcoma in children. Of these bladder-prostate ( ) is RMS BP RMS one of the most common primary sites. Treatment of these has recently revolved predominantly around chemotherapy with adjunct radiotherapy. Surgical excision is reserved for non responding cases. We present the case of a 2 year old boy with BP RMS who had a turbulent course during treatment, complicated by obstructive uropathy, recurrent urinary tract infections with febrile neutropenia episodes and non response to chemotherapy and radiation. Obstructive uropathy and deranged renal functions secondary to pelvic tumors especially should be aggressively managed especially since these tumors are BP RMS highly chemo-sensitive and it is imperative to start cytotoxic, nephrotoxic agents as soon as possible. Recurrent is frequent UTI problem associated with external urinary drainages especially in presence of febrile neutropenia and in malignant cases; exteriorisation of the ureters is an excellent option to tide over the treatment period.